Mental health status of college students during coronavirus disease 2019 epidemic.

Objective To investigate the psychological characteristics of college students during the outbreak of coronavirus disease 2019 (COVID-19), so as to provide a basis for psychological intervention. Methods From May 17, 2020 to Jun. 17, 2020, the adjusted psychological questionnaires for emergent events of public health (PQEEPH) was surveyed among the college students of Beijing Union University. The questionnaire included 5 dimensions: depression, neurasthenia, fear, obsessive-compulsive anxiety, and hypochondriasis. Four grades were scored according to the degree and frequency of emotional responses: 0 means no symptoms, 1 means mild symptoms, 2 means moderate symptoms, and 3 means severe symptoms. Results A total of 3 019 valid questionnaires were collected. During the COVID-19 epidemic, the emotional responses of college students, from the most serious to the least, were fear, neurasthenia, depression, obsessive-compulsive anxiety, and hypochondriasis, with the incidences being 87.7% (2 648/3 019), 44.8% (1 353/3 019), 37.4% (1 129/3 019), 17.3% (522/3 019), and 11.6% (350/3 019), respectively. The fear scores of female students were higher than those of male students (P<0.001), the fear scores of college students from towns/suburbs were higher than those from rural and urban areas (both P<0.017), the scores of depression, neurasthenia and obsessive-compulsive anxiety of college students with confirmed COVID-19 cases around them or their relatives participated in the epidemic prevention and control as medical staff or logistics support personnel were higher than those without such conditions (all P<0.017), and the scores of depression, obsessive-compulsive anxiety and hypochondriasis of college students with suspected COVID-19 cases around them were higher than those without such condition (all P<0.017). Females were more likely to have moderate to severe fear than males (odds ratioOR=1.53, 95% confidence intervalCI1.25-1.88, P<0.001), those with confirmed or suspected COVID-19 cases around them were more likely to have moderate to severe fear than those without such conditions (OR=2.03, 95% CI 1.29-3.20, P=0.002), and those living in towns/suburbs were more likely to have moderate to severe fear than those living in rural and urban areas (OR=0.72, 95% CI 0.56-0.94, P=0.015;OR=0.78, 95% CI 0.63-0.97, P=0.025). Conclusion COVID-19 epidemic has impact on the psychology of college students. It is necessary to pay attention to the mental health of college students and provide targeted psychological counseling for them.Copyright © 2022, Second Military Medical University Press. All rights reserved.

Mental health status of college students during coronavirus disease 2019 epidemic

Objective To investigate the psychological characteristics of college students during the outbreak of coronavirus disease 2019 (COVID-19), so as to provide a basis for psychological intervention. Methods From May 17, 2020 to Jun. 17, 2020, the adjusted psychological questionnaires for emergent events of public health (PQEEPH) was surveyed among the college students of Beijing Union University. The questionnaire included 5 dimensions: depression, neurasthenia, fear, obsessive-compulsive anxiety, and hypochondriasis. Four grades were scored according to the degree and frequency of emotional responses: 0 means no symptoms, 1 means mild symptoms, 2 means moderate symptoms, and 3 means severe symptoms. Results A total of 3 019 valid questionnaires were collected. During the COVID-19 epidemic, the emotional responses of college students, from the most serious to the least, were fear, neurasthenia, depression, obsessive-compulsive anxiety, and hypochondriasis, with the incidences being 87.7% (2 648/3 019), 44.8% (1 353/3 019), 37.4% (1 129/3 019), 17.3% (522/3 019), and 11.6% (350/3 019), respectively. The fear scores of female students were higher than those of male students (P<0.001), the fear scores of college students from towns/suburbs were higher than those from rural and urban areas (both P<0.017), the scores of depression, neurasthenia and obsessive-compulsive anxiety of college students with confirmed COVID-19 cases around them or their relatives participated in the epidemic prevention and control as medical staff or logistics support personnel were higher than those without such conditions (all P<0.017), and the scores of depression, obsessive-compulsive anxiety and hypochondriasis of college students with suspected COVID-19 cases around them were higher than those without such condition (all P<0.017). Females were more likely to have moderate to severe fear than males (odds ratio[OR]=1.53, 95% confidence interval[CI]1.25-1.88, P<0.001), those with confirmed or suspected COVID-19 cases around them were more likely to have moderate to severe fear than those without such conditions (OR=2.03, 95% CI 1.29-3.20, P=0.002), and those living in towns/suburbs were more likely to have moderate to severe fear than those living in rural and urban areas (OR=0.72, 95% CI 0.56-0.94, P=0.015;OR=0.78, 95% CI 0.63-0.97, P=0.025). Conclusion COVID-19 epidemic has impact on the psychology of college students. It is necessary to pay attention to the mental health of college students and provide targeted psychological counseling for them.Copyright © 2022, Second Military Medical University Press. All rights reserved.

Molecular Detection of Canine Parvovirus-2c (Cpv-2c) in Diseased Coyote Pups (Canis Latrans) at Northeastern Mexico

Intro: Canine parvovirus type 2 (PVC-2), Protoparvovirus genus of the Parvoviridae family, is a worldwide distribution virus that affects the Canidae family. In free-living coyotes (Canis latrans), the presence of the PCV-2a, PCV-2b and PCV-2c subtypes of PVC-2 has been reported, but there are no reports of their presence as a cause of clinical damage. The objective of this study is to report the presence of PVC-2c in an outbreak of mild gastroenteritis in three coyote pups detected in northeastern Mexico Methods: During the fall of 2019, in the suburban area of Monterrey, N.L., 3 affected coyote pups were detected with a mild gastroenteric condition consisting of mild diarrhea with loose stools, vomiting, dehydration, loss of appetite, pale mucous membranes, and low weight. Stool samples were tested for Canine Parvovirus (CPV-2), Canine Coronavirus (CCV) or Giardia antigens with a commercial kit. All samples were positive for CPV-2 and these were subsequently analyzed by PCR and sequencing of the CPV-2 VP2 gene. Using bioinformatics, the VP2 gene sequence data obtained were used to establish phylogenetic relationships with homologous sequences reported in coyotes and CPV-2 vaccines. Finding(s): The genetic sequence of VP2 obtained showed a high homology (98.1 to 100%) with CPV-2c. The sequences obtained from the pups showed 100% homology to each other. The phylogenetic tree showed that the sequences reported in coyotes are grouped in different clades and that the sequence of the VP2 gene of CPV-2c from coyote pups is grouped in a different monophyletic group. Conclusion(s): Information suggests that wild coyotes may not only act as asymptomatic reservoir hosts but may also be clinically affected by PVC-2c. It is necessary to carry out studies to know the effects of the genetic subtypes of PVC-2 in the population of coyotes and other wild canids of northeastern Mexico.Copyright © 2023

The role of industrial zones in local development based on the example of the Wieliczka Economic Activity Zone (Poland)

The aim of the article is to present the role of economic activity zones in the development of local urban centres and their surroundings. The main area of research was the area of the town and commune of Wieliczka, with particular emphasis on the Wieliczka Economic Activity Zone (WEAZ). As part of the analysis, attention was focused primarily on the impact of enterprises on the labour market and the income of the commune. Based on the existing literature studies, the scale of multiplier effects resulting from the development of enterprises in WEAZ was also estimated. The presentation of the impact of companies located in the Wieliczka Economic Activity Zone on the socio-economic development of the commune area made it possible to determine the scale of benefits resulting from investing public funds in the creation of this type of investment zones. Analysing the role of WEAZ in the development of the local economy, the authors identified the relationship between the inflow of investments and a permanent increase in demand on the local labour market. This also concerned the resilience of newly created jobs in the context of the SARS-CoV-2 pandemic.

NOISE POLLUTION AND ARTERIAL HYPERTENSION

Environmental noise significantly impacts human health and well-being. It is a widespread problem in Europe, where at least one in five people are exposed to harmful levels of noise. Hearing loss is the most known health effect related to noise exposure. There is, however, growing data that links noise exposure to hypertension, coronary artery disease, and stroke. According to some theories, this relationship may be explained by the indirect pathway of noise exposure, which can cause sympathetic and endocrine activation, as well as several cognitive and emotional responses, including annoyance. Noise exposure leads to stress reactions independent of cognitive involvement. There is a possibility that noise exerts its effects directly through synaptic interactions, as well as through cognitive and emotional effects. Epidemiological studies indicate that nocturnal noise exposure has more profound health consequences. Nighttime noise exposure is associated with an increase in heart rate due to sympathetic activation or parasympathetic withdrawal, and with an increase in blood pressure as well as endothelial dysfunction. Hypertension is a common condition and is an important risk indicator for other cardiovascular diseases. Previous studies showed an association between noise exposure, blood pressure and arterial hypertension. Meta-analysis of cross-sectional studies found an increase of hypertension prevalence per 10 dB increase in daytime average road traffic noise level. There is, however, some heterogeneity among these studies. Prospective studies have also found an association between aircraft noise exposure and hypertension, supporting the cross-sectional findings. The analyses, of data from the large Hypertension and Exposure to Noise near Airports (HYENA) study, showed that an increase in nocturnal aircraft noise exposure per 10 dB was associated with an increased incidence of hypertension. The meaningful effect of night-time aircraft noise on arterial hypertension was also observed in the prospective observation of the subset of individuals from that study. In a longitudinal observation of 420 participants, higher aircraft noise exposure during the night significantly associated with the incidence of hypertension. Previous cross-sectional case-control study conducted in 2015, in 2 suburban areas of Krakow, Poland, revealed an increase in blood pressure and arterial stiffness as determined by carotid - femoral pulse wave velocity in individuals exposed to increased aircraft noise levels. However, even short-term noise reduction, as experienced during the COVID-19 lockdown, may reverse those unfavorable effects. As a result of these observations, noise mitigation strategies are important for cardiovascular health.

Effects of emission sources on the particle number size distribution of ambient air in the residential area

Particle size distribution is a major factor in the health and climate effects of ambient aerosols, and it shows a large variation depending on the prevailing atmospheric emission sources. In this work, the particle number size distributions of ambient air were investigated at a suburban detached housing area in northern Helsinki, Finland, during a half-year period from winter to summer of 2020. The measurements were conducted with a scanning mobility particle sizer (SMPS) with a particle size range of 16–698 nm (mobility diameter), and the events with a dominant particle source were identified systematically from the data based on the time of the day and different particle physical and chemical properties. During the measurement period, four different types of events with a dominant contribution from either wood-burning (WB), traffic (TRA), secondary biogenic (BIO), or long-range transported (LRT) aerosol were observed. The particle size was the largest for the LRT events followed by BIO, WB, and TRA events with the geometric mean diameters of 72, 62, 57, and 41 nm, respectively. BIO and LRT produced the largest particle mode sizes followed by WB, and TRA with the modes of 69, 69, 46, and 25 nm, respectively. Each event type had also a noticeably different shape of the average number size distribution (NSD). In addition to the evaluation of NSDs representing different particle sources, also the effects of COVID-19 lockdown on specific aerosol properties were studied as during the measurement period the COVID-19 restrictions took place greatly reducing the traffic volumes in the Helsinki area in the spring of 2020. These restrictions had a significant contribution to reducing the concentrations of NOx and black carbon originating from fossil fuel combustion concentration, but insignificant effects on other studied variables such as number concentration and size distribution or particle mass concentrations (PM1, PM2.5, or PM10). © 2022 The Authors

Enhanced natural releases of mercury in response to the reduction in anthropogenic emissions during the COVID-19 lockdown by explainable machine learning

The wide spread of the coronavirus (COVID-19) has significantly impacted the global human activities. Compared to numerous studies on conventional air pollutants, atmospheric mercury that has matched sources from both anthropogenic and natural emissions is rarely investigated. At a regional site in eastern China, an intensive measurement was performed, showing obvious decreases in gaseous elemental mercury (GEM) during the COVID-19 lockdown, while it was not as significant as most of the other measured air pollutants. Before the lockdown, when anthropogenic emissions dominated, GEM showed no correlation with temperature and negative correlations with wind speed and the height of the boundary layer. In contrast, GEM showed significant correlation with temperature, while the relationship between GEM and the wind speed/boundary layer disappeared during the lockdown, suggesting the enhanced natural emissions of mercury. By applying a machine learning model and the SHAP (SHapley Additive exPlanations) approach, it was found that the mercury pollution episodes before the lockdown were driven by anthropogenic sources, while they were mainly driven by natural sources during and after the lockdown. Source apportionment results showed that the absolute contribution of natural surface emissions to GEM unexpectedly increased (44 %) during the lockdown. Throughout the whole study period, a significant negative correlation was observed between the absolute contribution of natural and anthropogenic sources to GEM. We conclude that the natural release of mercury could be stimulated to compensate for the significantly reduced anthropogenic GEM via the surface-air exchange in the balance of mercury.

Racial and socioeconomic disparities in telemedicine use among US patients initiating cancer treatment during the COVID-19 pandemic

Background: The COVID-19 pandemic was associated with declines in in-person clinical visits. While telemedicine visits have increased, uptake has varied. Here we assess demographic and socioeconomic factors associated with telemedicine use among patients initiating treatment for 21 common cancers at community oncology clinics. Methods: This retrospective study uses the nationwide Flatiron Health electronic health record-derived de-identified database of patients with cancer. Patient characteristics were determined using structured and unstructured data curated via technology-enabled ion. We included patients (≥ 18 years) who initiated first-line cancer treatment between March 2020 and September 2021 (follow-up through December 2021). We focused on differences in telemedicine use (≥ 1 telemedicine visit within 90 days after treatment initiation) across race/ethnicity, insurance coverage, rurality (per Rural-Urban Commuting Areas), and socioeconomic status (SES). SES was defined using census block group data from the American Community Survey (2015-2019) (quintiles representing least to most affluent areas) based on patient addresses and measured using the Yost Index (incorporating income, home values, rental costs, poverty, blue-collar employment, unemployment, and education information). We used logistic regression models adjusted for clinical characteristics (i.e., age, sex, performance status, and stage) to examine differences in telemedicine use. Results: This study included 24,164 patients (48.1% women, median age: 69 [interquartile range: 61-77] years), of whom 15.9% used telemedicine services. Black patients were less likely to use telemedicine services than White patients (11.4% vs. 15.6%, odds ratio [OR] 0.69 [95% confidence interval [CI]: 0.59-0.79], p<0.01). Telemedicine use was also lower among patients without documented insurance than well-insured (commercial and Medicare payers) patients (10.7% vs. 15.9%, OR 0.62 [95% CI: 0.54-0.72], p<0.01). Those in rural (9.8%, OR 0.51 [95% CI: 0.45- 0.58], p<0.01) and suburban areas (13.1%, OR 0.71 [95%: 0.64-0.79], p<0.01) were less likely to use telemedicine services than patients in urban areas (17.6%). Finally, patients in the least affluent areas had lower telemedicine use than those in the most affluent areas (10.2% vs. 24.3%, OR 0.35 [95% CI: 0.31-0.40], p<0.01). Conclusions: During the COVID-19 pandemic, nearly one-fifth of patients initiating cancer treatment used telemedicine services. However, there were substantial disparities: Black, uninsured, non-urban, and less affluent patients are less likely to use telemedicine services. While telemedicine may expand access to specialty care, the proliferation of these services may widen cancer care disparities if vulnerable populations do not have equitable access.

Needs Assessment for Physical Activity Information During COVID-19 Among a Nationally Representative Sample of Parents and Children Ages 6-17 in the United States: A Cross-sectional Study

Background: The COVID-19 pandemic presented novel barriers to physical activity engagement for children and their families. Identifying what resources parents and children are interested in receiving can support efforts to mitigate the negative impact of the pandemic on youth physical activity behavior. This study aimed to identify physical activity-related information needs during the COVID-19 pandemic among a nationally representative sample of parents of children ages 6-10 and parent-child dyads of children ages 11-17. Methods: A crosssectional survey was conducted by a market research company (YouGov) in October-November 2020. Weighted percentages and corresponding 95% confidence intervals were calculated for information needs around physical activity, overall and by parent and child demographics. Parents were asked about their interest in information about helping their family be physically active during the pandemic, and children were asked about their own interest in information about being physically active. Results: Final analytic sample was 1000 parents (55.4% female;74.7% White;74.0% non-Hispanic);500 children ages 11-17 (52.1% male;77.6% White;77.4% non-Hispanic). Over 40% of parents and children were interested in information about being active during the pandemic [41.9% (95% CI: 38.9%-45.5%) and 41.5% (95% CI: 36.5%-46.7%), respectively]. Parents were more likely to be interested in information if they worked from home compared to outside the home [53.3% (95% CI: 43.3%-63.0%) versus 22.0% (95% CI: 14.9%-31.3%), respectively];had children attending school remotely compared to in-person [47.3% (95% CI: 40.2%-54.5%) versus 27.5% (95% CI: 19.6%-37.1%), respectively];and lived in a big city (66.5%;95% CI: 54.5%-76.7%) compared to a suburban area (42.5%;95% CI: 34.2%-51.2%), small town (34.6%;95% CI: 22.8%-48.8%), or rural area (34.1%;95% CI: 22.8%-47.6%). Children most interested were those who did not have resources for online activity engagement (65.3%;95% CI: 51.8%-76.7%), and those worried about their safety (55.2%;95% CI: 44.4%-65.6%) or getting infected with COVID-19 (57.8%;95% CI: 49.5%-65.6%). Children were also more likely to be interested in information if their parents worked full-time compared to not working [48.6% (95% CI: 41.7%-55.6%) versus 31.5% (95% CI:24.1%-39.9%), respectively], and lived in big city compared to a rural area [57.2% (95% CI: 45.3%-68.3%) versus 27.8% (95% CI: 17.8%-40.7%)]. Conclusion: Families most interested in physical activity-related resources were those whose organized activity opportunities may have been disrupted by the pandemic. Identifying felt needs is an important step in developing tailored interventions that effectively and sustainably support families in promoting activity among youth. Behavioral interventions oriented around increasing youth physical activity should provide guidance that resonates with families and accounts for setting-specific constraints and stressors.

RATES OF FIREARM-RELATED INJURIES IN CHILDREN DURING COVID

Purpose of Study Firearm violence comprises a large percentage of pediatric injuries within the United States. Among all highincome countries, 91% of childhood firearm deaths occur in US children younger than 14 years. Coronavirus-19 Pandemic is associated with increased firearm violence, but little is known about the impact on children. Our objective is to evaluate the pediatric rates of firearm-related injuries within the state of Connecticut (CT) before- and during-COVID. Methods Used Data was ed from the Connecticut Health Information Management Exchange (CHIME) datasets from 2016-2020. All cases of firearm related injuries were identified by ICD -10 codes. Two study groups were created using events occurring in 2018 and 2019 (before-COVID) and events occurring in 2020 (during COVID). Before and during COVID groups were compared to assess differences in rates of injuries and any associations by age, sex, race, cause of injury, bodily location of injury, and geographic location of event. Summary of Results A total of 188 encounters were identified. The mean age was 14 years (SD+/- 3.5), 20% girls, 80% boys, 43% White, 37% Black, and 12% Hispanic. The overall rate of firearm injuries before COVID was 1.6 per 100,000 and during COIVD was 2.1/100,000 (p<0.01). Adjusting for population changes, the incidence of firearm injuries in CT increased by 33%. White and Black children accounted for similar proportion of injuries in all time periods. In all years, about 80% were unintentional while half were injured in suburban areas compared to urban and rural (p=0.97). Almost half of all injuries involved an extremity. Conclusions The proportion of children with firearm related injuries significantly increased during COVID compared to the preceding two years. The age, sex and race/ethnicity of injured children was similar before and during the COVID-19 pandemic. Unintentional injury accounted for the majority of injuries. Overall the proportion of White and Black children injured by firearms was similar, and children living in suburban areas were injured more than other areas. (Table Presented).

Harnessing Telemedicine to Improve Access to Care During the COVID-19 Pandemic

Objective: Before COVID-19, telemedicine had gained traction as a clinical tool, which was reflected by the adoption of new billing codes. Here we report outcomes in our Endocrine practice, which rapidly switched to exclusively tele-health in March 2020 with no pre-existing systems or protocols for this transition. We hypothesized that barriers to care, including patients’ health literacy, access to technology/internet, and access to remote monitoring tools such as blood pressure cuffs and weight scales, would make the transition to tele-health less successful in a low-income urban setting than in the suburbs. Methods: We measured show rates at Temple Endocrinology outpatient clinic sites using the CPT coding system to compare all scheduled appointments with all completed visits. We selected periods from April 1st to July 31st of 2019 and the same dates in 2020, because outpatient visits were exclusively in-person (2019) or exclusively tele-health (2020). Appointments included both faculty and fellow clinics. Data were stratified by service location amongst four major clinic sites that serve patients of different socioeconomic and ethnic backgrounds – namely, Temple University Hospital (TUH) in North Philadelphia, an urban federally designated medically underserved area, Temple Fort Washington (FW) serving a high-income suburban area, Temple Center City (CC) serving a high-income urban area, and Temple Jeanes, serving a middle-income suburban area. Results: Surprisingly, the proportion of completed outpatient visits at TUH increased from 68.2% (n = 2,965/4,346) in 2019 to 72.9% (n = 2,997/4,109) in 2020 (p = 0.00001), with an absolute increase of 1.01% in our completed encounters. In contrast, at FW, the proportion of completed outpatient visits decreased from 89.8% (n = 378/421) in 2019 to 79.3% (n =211/266) in 2020 (p = 0.00014). At CC, 90.2% (n = 342/379) visits were completed in 2019 and 89.5% (n = 366/409) in 2020 (p = 0.73). At Jeanes, rates were 75.8% (n = 485/640) in 2019 and 76.7% (n = 615/802) in 2020 (p = 0.69). Discussion/Conclusion: Despite the speed with which we transitioned to an entirely tele-health-based practice at the start of the pandemic, we found that we were equally – if not more able – to complete clinical Endocrinology visits with our population of underserved patients in North Philadelphia. In contrast, at our suburban FW campus, the show rates fell. We are currently examining disease acuity, transportation issues related to in-person visits, and internet access through smartphones in the populations served by TUH and FW. Overall, our data suggest that tele-health can be a successful option for Endocrine practice in an underserved urban area.

Psychosocial aspects in relation to clinica status of breast cancer patients after prolonged COVID pandemic in south India: A observational survey study

Background: The prolonged global threat imposed by covid 19 pandemic's first and second wave has created immense stress among the breast cancer due to interruptions of standard oncological care. The frequent lockdown imposed had tremendous impact on the patients' financial status and posed hinderance in transportation to oncological centre. In our hospital, majority of the treatment population are from distant places and below poverty line. We conducted a questionnaire based study to assess the psychological impact in this situation affecting their quality of life(QOL) and their perspective in this current situation. MATERIALS AND METHODS:Breast cancer patients who had been diagnosed and registered in our department from 1st January to 1stApril 2020 before the covid out break were tracked from the medical records. The patients details, disease status dates of follow up and the treatment details were collected.Defaulted patients were contacted.Post one year, in April 2021, these patients were assessed clinically and questioned regarding the treatment perspective. Psychological status and health related quality of life were analysed with GAD-7 (Generalised anxiety disorder questionnaire), PHQ-9 (patient health questionnaire) and EORTC QLQ-C30 questionnaire. Results:A total of 202 breast cancer patients were included. 83 patients(41%) were diagnosed with early breast cancer of which 67(33%) patients were started on Sadjuvant chemotherapy after surgery, 16 (8%)were registered for hormonal therapy. 54(27%) patients with locally advanced, were on neoadjuvant chemotherapy. 65(32%)had metastatic disease at presentation. 23 of 65 metastatic patients were in visceral crisis and were on supportive management for the same. 35 patients had been started on palliative chemotherapy. Out of the 156 patients who had been in initiated with various chemotherapy, only 62(31%) patients were able to review at correct interval for the scheduled chemotherapy. 45 patients(22%) reviewed in the day care irregularly. Among the 45, 28 patients had locally advanced breast cancer and 22 patients had clinical progression due to prolonged gap. 38 patients(19%) had defaulted completely.Of the 38, 16 had advanced disease and presented with clinical progression of disease and switched to second line chemotherapy. 15 patients progressed to have distant metastases and are started on palliative chemotherapy or supportive care. 7 patients who were on adjuvant chemotherapy are kept under close follow up. 11 patients with metastatic breast cancer had died during the past one year. 3 patients had committed suicide.112(55 %) patients were within the city. 71 patients(35%) were from suburban areas. 19 patients(10%) were from adjacent rural areas. 113(56%) were educated.176 (87 %) were desperate to continue treatment inspite of pandemic, while remaining patients main concern was to avoid infection than to get oncological management. While the most common reason for defaulting was travel restrictions, few also documented financial issues and ignorance about progression of cancer. 46 (22%)of patients who had been visiting the day care had turned covid positive. Except for 2 patients who succumbed to the infection, none had major complications. 51%, 42%, 7% had mild, moderate and severe anxiety. 69%, 25%, 6% had mild, moderate and severe depression. The severe anxiety and depression was significant with metastatic breast cancer and educated patients. There were 3 suicides. The overall heath score had a mean of 4. The overall QOL had a mean score of 3 (1-very poor to 7-excellent). CONCLUSION: In patients who were already psychologically affected by onset of cancer, the chaos created by the pandemic added to it further. Hence the patients also need counseling appropriately during oncological treatment.

30th Annual Scientific Meeting of Indonesian Heart Association (ASMIHA)

The proceedings contain 200 papers. The topics discussed include: an ultra-rare case of Hutchinson-Gilford progeria syndrome with severe aortic regurgitation due to bicuspid aortic valve in a 9-year-old girl;pulse dose corticosteroid improves clinical outcome in pulmonary hypertension patient: a potential of immense affordability and availability medication in suburban area;infected femoral artery pseudoaneurysm with klebsiella pneumoniae bacteremia in injected drug abuser: a case report;cardiac complications in immunocompromised patient : a case report;cardiac arrest in COVID-19 patient presenting with takotsubo cardiomyopathy;cardiac amyloidosis: a great pretender of left ventricular hypertrophy with systemic manifestation;and managing acute decompensated heart failure with exacerbation of chronic obstructive pulmonary disease in rural area: a case report.